Cancer Genomics

Cancer Nanotechnology

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Nanotechnology is increasingly finding use in the management of cancer. Nanoscale devices have impacted cancer biology at three levels: early detection using, for example, Nano cantilevers or nanoparticles; tumour imaging using radio contrast nanoparticles or quantum dots; and drug delivery using nanovectors and hybrid nanoparticles. This review addresses some of the major milestones in the integration of nanotechnology and cancer biology, and the future of nanoscale approaches for cancer management. The drivers for advances in nanotechnology have been the development of tools that enable us to manipulate at an atomic scale, and materials and chemistry that allow the constructions of novel structures. Although it is not the focus of this review to address these tools in details, it is important to realise potentials of these analytical and fabrication tools, which if integrated with fundamental biology can provide essential breakthroughs in the fight against cancer. Nanotechnology platforms can provide the unique niche within this space by enabling multimodal delivery with a single application. Another emerging direction in the application of nanotechnology in cancer is the use of self-assembly techniques, such as to design monodisperse delivery vehicles like polymerosomes or to develop sensors.