New Frontiers in Gene Editing
Gene editing is rapidly progressing from being a research/ screening tool to one that promises important applications downstream in drug development, cell therapy and bioprocessing. • Genome editing (e.g., CRISPRs technology to replace defective DNA with “good” DNA) is now a new trend in 2016. The engineered editing system makes use of an enzyme that nicks together DNA with a piece of small RNA that guides the tool to where researchers want to introduce cuts or other changes in the genome.
- Nucleic Acid based Editing: RNA Editing
- RNAi Engineering
- Editing of m-RNA
- Cas-9 application in RNA Modification
- Single Cell Cancer Genomics
- Genetics and genomics of cancer immunity and immunotherapy
- Intra-tumoural and inter-tumour heterogeneity
- ctDNA
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